Search results for "digestive tract"

showing 10 items of 48 documents

Health-Related Quality of Life Issues Experienced by Thoracic and Breast Sarcoma Patients: A Rare and Understudied Group

2021

Thoracic and breast sarcomas constitute a rare subgroup within the sarcoma population. There is limited knowledge about their health-related quality of life (HRQoL) and a valid disease-specific HRQoL instrument is lacking. This qualitative study aimed to investigate the HRQoL issues experienced by a small group of thoracic and breast sarcoma patients. Semi-structured interviews with 19 thoracic and four breast sarcoma patients were conducted and thematically analysed. Physical issues mentioned by both groups were fatigue, sleep disturbances, pain, wound infections, and symptoms related to chemotherapy and radiotherapy. Tightness in the back and restrictions in performing tasks above arm hei…

medicine.medical_specialtychest sarcomaBreast SarcomaPopulationbreast sarcomaSocial issuesArticleRC0254Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]All institutes and research themes of the Radboud University Medical CenterSDG 3 - Good Health and Well-beingQuality of lifemedicinethoracic sarcomaSocial determinants of healtheducationeducation.field_of_studybusiness.industryRGeneral Medicinemedicine.diseaseMental healthhealth-related quality of lifeMoodpatient-reported outcomesPhysical therapyMedicineSarcomabusinessRare cancers Radboud Institute for Health Sciences [Radboudumc 9]Journal of Clinical Medicine
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Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

2019

Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery.A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a c…

Malerenal failureTime Factorsmedicine.medical_treatmentAdult; Aged; Anti-Inflammatory Agents Non-Steroidal; Elective Surgical Procedures; Female; Humans; Ileus; Kaplan-Meier Estimate; Male; Middle Aged; Patient Safety; Postoperative Care; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Colectomy; ProctectomyAnti-Inflammatory Agentscolorectal surgery; ileus; non-steroidal anti-inflammatory drugs; NSAIDSKaplan-Meier Estimate030230 surgeryTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicinePostoperative ComplicationsProspective StudiesProspective cohort studyColectomyColorectalColectomyRISKProctectomyHazard ratioAnti-Inflammatory Agents Non-SteroidalAcute kidney injuryMiddle AgedColorectal surgeryNSAIDTreatment OutcomeElective Surgical Procedures030220 oncology & carcinogenesisFemalePatient SafetyNon-SteroidalCohort studyAdultcolorectal Surgery ileus non-steroidal anti-inflammatory drugsmedicine.medical_specialtyIleusNon‐steroidal anti‐inflammatory drugs. NSAIDs. Postoperative ileus. Colorectal surgery.ACUTE KIDNEY INJURYanti-inflammatory agents03 medical and health sciencesIleusInternal medicinemedicineHumansAdverse effectAgedProportional Hazards Modelsnon-steroidal anti-inflammatory drugs - ileus - colorectal surgeryPostoperative Carebusiness.industryRecovery of Functionmedicine.diseaseSettore MED/18 - Chirurgia Generalecolorectal cancer.Surgerycolorectal surgerybusiness
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Oral trichomonosis: Description and severity of lesions in birds in Spain.

2020

Este artículo se encuentra disponible en la página web de la revista en la siguiente URL: https://www.sciencedirect.com/science/article/abs/pii/S1383576920301264 This is the pre-peer reviewed version of the following article: Martínez-Herrero, M.C., Sansano-Maestre, J., Ortega, J., González, F., López-Márquez, I., Gómez-Muñoz, M.T. et al. (2020). Oral trichomonosis: description and severity of lesions in birds in Spain. Veterinary Parasitology, vol. 283, art. 109196, which has been published in final form at https://doi.org/10.1016/j.vetpar.2020.109196. Este es el pre-print del siguiente artículo: Martínez-Herrero, M.C., Sansano-Maestre, J., Ortega, J., González, F., López-Márquez, I., Góme…

ColumbiformesTricomoniasis.PhysiologyTrichomonas InfectionsTrichomonas gallinaeUpper digestive tractBirds - Communicable diseases.medicineAnimalsColumbidaeTrichomoniasis.TrichomoniasisGeneral VeterinarybiologyRaptorsBird DiseasesGeneral MedicineAves - Enfermedades infecciosas.biology.organism_classificationmedicine.diseaseSkullmedicine.anatomical_structureStrigiformesSpainParasitic diseaseAccipitriformesTrichomonasParasitologyBirds - Parasites.Aves - Parásitos.Veterinary parasitology
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Detection of laryngeal squamous cell carcinoma in a context of acrokeratosis paraneoplastica: Case report

2018

Background: Acrokeratosis paraneoplastica is an infrequent paraneoplastic disease in which cutaneous lesions appear and develop in a context of an underlying malignancy. Upper aerodigestive tract carcinomas are the most common neoplasias associated with this syndrome. The aim of this report is to raise awareness of this syndrome, since the recognition of the skin lesions could allow suspicion and diagnosis of the underlying neck malignancy at an early curable stage. Methods: We report a case of a 62-year-old life-long smoking male who presented a several months evolution of multiple skin lesions, affecting both ear lobes, hands and feet. He was referred for appropriate diagnosis and treatme…

medicine.medical_specialtybusiness.industryParaneoplastic diseaseContext (language use)Malignancymedicine.diseaseLaryngeal squamous cell carcinomalcsh:OtorhinolaryngologyDermatologylcsh:RF1-547030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineUpper aerodigestive tractOtorhinolaryngology030220 oncology & carcinogenesismedicineAcrokeratosis paraneoplasticaStage (cooking)Skin lesionbusinessOtolaryngology Case Reports
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Occupation and risk of upper aerodigestive tract cancer: The ARCAGE study

2012

We investigated the association between occupational history and upper aerodigestive tract (UADT) cancer risk in the ARCAGE European case-control study. The study included 1,851 patients with incident cancer of the oral cavity, oropharynx, hypopharynx, larynx or esophagus and 1,949 controls. We estimated odds ratios (OR) and 95% confidence intervals (CI) for ever employment in 283 occupations and 172 industries, adjusting for smoking and alcohol. Men (1,457 cases) and women (394 cases) were analyzed separately and we incorporated a semi-Bayes adjustment approach for multiple comparisons. Among men, we found increased risks for occupational categories previously reported to be associated wit…

AdultMaleRiskCancer Researchmedicine.medical_specialtyEsophageal NeoplasmsEsophageal Neoplasms/epidemiologyOral cavityEurope/epidemiologyPharyngeal Neoplasms/epidemiologyRisk FactorsNeoplasmsmedicineHumansUADT cancer riskOccupationsLaryngeal Neoplasmsddc:613AgedMouth neoplasmbusiness.industryConstruction IndustryCase-control studyCancerPharyngeal NeoplasmsOdds ratioLaryngeal Neoplasms/epidemiologyMiddle Agedmedicine.diseaseConfidence intervalSurgeryEuropeUpper aerodigestive tractOncologyConstruction industryCase-Control StudiesFemaleMouth NeoplasmsbusinessNeoplasms/epidemiologyMouth Neoplasms/epidemiologyDemography
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Description of a new species: Dorylaimus parasiticus , a parasite of amphibians in the Iberian Peninsula (Nematoda: Dorylaimida)

1995

Dorylaimus parasiticussp. nov. (Nematoda: Dorylaimidae) si described from the digestive tract and general body cavity of Salamandra salamandra, Rana perezi, and Bufo bufo, amphibians of the Iberian Peninsula (Spain). This is the first record of a member of the Order Dorylaimida size, a thick transversely striated body cuticle with 20 to 26 longitudinal ridges.

geographygeography.geographical_feature_categorybiologyEcologyDorylaimidabiology.organism_classificationmedicine.anatomical_structurePeninsulamedicineDorylaimusParasite hostingAnimal Science and ZoologyDigestive tractSalamandraBufoBody cavityEcology Evolution Behavior and SystematicsJournal of Zoology
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Proposed new grading of oral submucous fibrosis based on cheek flexibility.

2013

Objectives: Oral submucous fibrosis (OSMF) is a potentially malignant disorder of oral cavity, pharynx and upper digestive tract, characterized by progressive inability to open the mouth. Based on clinical and/or histopathological features, various classifications and grading systems have been put forth till date. The aim of the present study was to study the variance in cheek flexibility in OSMF patients, the observance of which led to the introduction of a new grading for the condition. Material and Methods: The study included 412 patients with OSMF attending to the Department of Oral Medicine and Radiology during the period from December 2008 to June 2013. A detailed history and examinat…

Pathologymedicine.medical_specialtyOral Medicine and Pathologybusiness.industryResearchPharynxDentistryOdontologíaCheekMalignancymedicine.disease:CIENCIAS MÉDICAS [UNESCO]Upper digestive tractCiencias de la saludstomatognathic diseasesmedicine.anatomical_structureOral submucous fibrosisstomatognathic systemUNESCO::CIENCIAS MÉDICASmedicineEtiologybusinessGeneral DentistryGrading (tumors)Oral medicineJournal of clinical and experimental dentistry
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Rupture of supra-aortic neck arteries due to lesions caused by tracheal tubes

1984

Haemorrhages from the common carotid or innominate artery caused by tracheal tubes are rare but dramatic complications of head and neck surgery. Patients with metal tracheostomy cannulas or patients in the phase of wound healing after radical tumour resections of the pharynx and larynx run a greater risk. Following extensive tumour resections and radiation of the upper respiratory and digestive tracts in 680 patients, acute bleeding of the larger neck arteries occurred in 18 patients. In four of these cases, fistulae developed in the innominate or common carotid artery. These ruptures were caused by both plastic and metal tracheal tubes.

AdultMaleLarynxmedicine.medical_specialtyHemorrhagePostoperative Complicationsmedicine.arteryIntubation IntratrachealmedicineHumansCommon carotid arteryRespiratory systemLaryngeal NeoplasmsBrachiocephalic TrunkAgedRupturebusiness.industryPharynxGeneral MedicineMiddle AgedSurgerymedicine.anatomical_structureOtorhinolaryngologyHead and neck surgeryDigestive tractCarotid Artery InjuriesbusinessAortic neckArteryThe Journal of Laryngology & Otology
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Patterns and determinants of adherence to resistance and endurance training during cancer treatment in the Phys-Can RCT.

2022

Abstract Background Knowledge regarding adherence is necessary to improve the specificity of exercise interventions during cancer treatment. We aimed to determine adherence to resistance and endurance training interventions in parallel; identify subgroups with similar adherence characteristics; and examine determinants of these subgroups. Methods In the Phys-Can randomised controlled trial, participants (n = 577, 81% women, mean(SD) age 59(12) years, and 50% with BMI ≥ 25 kg/m2) starting (neo-) adjuvant treatment for breast, colorectal or prostate cancer were randomized to 6-month of high (HI) or low-to-moderate intensity (LMI) supervised, group-based resistance training and individual home…

IdrottsvetenskapRehabilitationPhysical Therapy Sports Therapy and RehabilitationResistance trainingEndurance trainingTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]All institutes and research themes of the Radboud University Medical CenterAdherenceFITT principlesOrthopedics and Sports MedicineVDP::Medisinske Fag: 700PatternsExerciseDeterminantsSport and Fitness SciencesCancerBMC sports science, medicinerehabilitation
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Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With L…

2020

Contains fulltext : 220040.pdf (Publisher’s version ) (Closed access) BACKGROUND & AIMS: Lynch syndrome is caused by variants in DNA mismatch repair (MMR) genes and associated with an increased risk of colorectal cancer (CRC). In patients with Lynch syndrome, CRCs can develop via different pathways. We studied associations between Lynch syndrome-associated variants in MMR genes and risks of adenoma and CRC and somatic mutations in APC and CTNNB1 in tumors in an international cohort of patients. METHODS: We combined clinical and molecular data from 3 studies. We obtained clinical data from 2747 patients with Lynch syndrome associated with variants in MLH1, MSH2, or MSH6 from Germany, the Net…

0301 basic medicineOncologyMaleColorectal cancerDNA Mutational Analysisgenetic analysisHEREDITARYcancer riskGUIDELINESDNA Mismatch Repair0302 clinical medicineGermanyTumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14]Prospective Studiesprognostic factorFinlandbeta CateninNetherlandsOutcomePrognostic FactorGastroenterologyGenetic AnalysisColonoscopyMiddle AgedCANCERLynch syndromeCancer Risk3. Good healthDNA-Binding ProteinsDEFICIENCYMutS Homolog 2 Proteinsyöpägeenitoutcome030211 gastroenterology & hepatologyDNA mismatch repairFemaleMutL Protein Homolog 1geenitutkimusAdenomaAdultmedicine.medical_specialtycongenital hereditary and neonatal diseases and abnormalitiesAdenoma3122 CancersAdenomatous Polyposis Coli ProteinINSTABILITYSOCIETYMLH103 medical and health sciencesInternal medicinemedicineMANAGEMENTHumansLynchin oireyhtymäneoplasmspaksusuolisyöpäHepatologybusiness.industryCancernutritional and metabolic diseasesennusteetmedicine.diseaseColorectal Neoplasms Hereditary Nonpolyposisdigestive system diseasesMSH6030104 developmental biologyMSH2Mutationbusiness
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